Piperine suppresses pyroptosis and interleukin-1β release upon ATP triggering and bacterial infection

• Main Authors: Yi-Dan Liang (Author), Wen-Jing Bai (Author), Chen-Guang Li (Author), Li-Hui Xu (Author), Hong-Xia Wei (Author), Hao Pan (Author), Xian-Hui He (Author), Dong-Yun Ouyang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Piperine is a phytochemical present in black pepper (Piper nigrum Linn) and other related herbs, possessing a wide array of pharmacological activities including anti-inflammatory effects. Previously, we demonstrated that piperine has therapeutic effects on bacterial sepsis in mice, but the underlyin...