High resolution melting curve analysis, a rapid and affordable method for mutation analysis in childhood acute myeloid leukemia

• Váldodahkkit: Yin eLiu (Dahkki), Jingyan eTang (Dahkki), Peter eWakamatsu (Dahkki), Huiliang eXue (Dahkki), Jing eChen (Dahkki), Paul S Gaynon (Dahkki), Shuhong eShen (Dahkki), Weili eSun (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2014-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background: Molecular genetic alterations with prognostic significance have been described in childhood acute myeloid leukemia (AML). The aim of this study was to establish cost-effective techniques to detect mutations of FMS-like tyrosine kinase 3 (FLT3), Nucleophosmin 1 (NPM1), and a partial tande...