OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall's plaque formation

• Main Authors: Zewu Zhu (Author), Fang Huang (Author), Yingcheng Jiang (Author), Shuhao Ruan (Author), Minghui Liu (Author), Youjie Zhang (Author), Yongchao Li (Author), Jinbo Chen (Author), Yu Cui (Author), Zhiyong Chen (Author), Hequn Chen (Author), Feng Zeng (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Randall's plaques (RP) are identified as anchored sites for kidney calcium oxalate stones, but the mechanism remains unclear. Given the importance of osteogenic-like cells in RP formation and OCT4 in reprogramming differentiated cells to osteoblasts, the current study explor...