Molecular Pathogenesis of Desmoid Tumors

Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors in which beta-catenin/TCF3 mediated Wnt signaling is activated. More than 80% of desmoid tumors contain activating mutations in ß-Catenin which leads to up-regulation of ß-Catenin. The functional con...

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Bibliographic Details
Main Authors: S Amini Nik (Author), K Van Dam (Author), A Jadidizadeh (Author), S Tejpa (Author), JJ Cassiman (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2005-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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