Purinergic P2Y2 and P2X4 Receptors Are Involved in the Epithelial-Mesenchymal Transition and Metastatic Potential of Gastric Cancer Derived Cell Lines

• Main Authors: Mauricio Reyna-Jeldes (Author), Erwin De la Fuente-Ortega (Author), Daniela Cerda (Author), Erandi Velázquez-Miranda (Author), Katherine Pinto (Author), Francisco G. Vázquez-Cuevas (Author), Claudio Coddou (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer (GC) is a major health concern worldwide, presenting a complex pathophysiology that has hindered many therapeutic efforts so far. In this context, purinergic signaling emerges as a promising pathway for intervention due to its known role in cancer cell proliferation and migration. In...