Rutin protects against cyclophosphamide induced immunological stress by inhibiting TLR4-NF-κB-mediated inflammation and activating the Nrf2- mediated antioxidant responses

• Main Authors: Zhiwei Lan (Author), Hong Wang (Author), Shuqi Wang (Author), Tong Zhu (Author), Siqi Ma (Author), Yang Song (Author), Cancan Cui (Author), Mingchun Liu (Author), Chunlian Tian (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rutin exists in many plants and has many pharmacological effects, including antioxidant, anti-inflammatory, antibacterial and immune regulation. In this study, the immunomodulatory and antioxidant effects of rutin were revealed by cyclophosphamide (CTX) induced mice model. The expression level of th...