High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

• Main Authors: Chun-Xia Yi (Author), Matthias H. Tschöp (Author), Stephen C. Woods (Author), Susanna M. Hofmann (Author)
• Formato: Livro
• Publicado em: The Company of Biologists, 2012-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

SUMMARY The mediobasal hypothalamic arcuate nucleus (ARC), with its relatively 'leaky' blood-brain barrier that allows more circulating molecules to enter the brain, has emerged as a key sensor of blood-borne signals. In both the ARC and white adipose tissue (WAT), consumption of a high-fa...