Cytotoxic activity of crude extracts from Datura stramonium's fungal endophytes against A549 lung carcinoma and UMG87 glioblastoma cell lines and LC-QTOF-MS/MS based metabolite profiling

Cytotoxic activity of crude extracts from Datura stramonium's fungal endophytes against A549 lung carcinoma and UMG87 glioblastoma cell lines and LC-QTOF-MS/MS based metabolite profiling

Abstract Background Endophytic fungi are a proven source of bioactive secondary metabolites that may provide lead compounds for novel drug discovery. In this study, crude extracts from fungal endophytes isolated from Datura stramonium were evaluated for cytotoxic activity on two human cancer cell li...

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Main Authors: Kudzanai Ian Tapfuma (Author), Nkemdinma Uche-Okereafor (Author), Tendani Edith Sebola (Author), Raeesa Hussan (Author), Lukhanyo Mekuto (Author), Maya Mellisa Makatini (Author), Ezekiel Green (Author), Vuyo Mavumengwana (Author)
Format: Book
Published: BMC, 2019-11-01T00:00:00Z.
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