NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease

Background and Aims. The nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) inflammasome has been implicated in the pathogenesis of chronic kidney disease (CKD); however, its exact role in glomerular injury and tubulointerstitial fibrosis is still undefined. The present study...

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Main Authors: Honglei Guo (Author), Xiao Bi (Author), Ping Zhou (Author), Shijian Zhu (Author), Wei Ding (Author)
Format: Book
Published: Hindawi Limited, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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