Physicochemical Characterizations and Pharmacokinetic Evaluation of Pentazocine Solid Lipid Nanoparticles against Inflammatory Pain Model

• Hoofdauteurs: Zaheer Ullah Khan (Auteur), Anam Razzaq (Auteur), Ahsan Khan (Auteur), Naeem Ur Rehman (Auteur), Hira Khan (Auteur), Taous Khan (Auteur), Ashraf Ullah Khan (Auteur), Norah A. Althobaiti (Auteur), Farid Menaa (Auteur), Haroon Iqbal (Auteur), Naveed Ullah Khan (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Pentazocine (PTZ), a narcotic-antagonist analgesic, has been extensively used in the treatment of initial carcinogenic or postoperative pain. Hepatic first-pass metabolism results in low oral bioavailability and high dose wastage. Herein, 10 mg (-)-Pentazocine (HPLC-grade) was incorporated to solid...