PCSK9: A Key Target for the Treatment of Cardiovascular Disease (CVD)
Proprotein convertase subtilisin/kexin type 9 (PCSK9), as a vital modulator of low-density lipoprotein cholesterol (LDL-C) , is raised in hepatocytes and released into plasma where it binds to LDL receptors (LDLR), leading to their cleavage. PCSK9 adheres to the epidermal growth factor-like repeat A...
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Tabriz University of Medical Sciences,
2020-08-01T00:00:00Z.
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