Dipeptide Repeat Pathology in <i>C9orf72</i>-ALS Is Associated with Redox, Mitochondrial and NRF2 Pathway Imbalance
The hexanucleotide expansion of the <i>C9orf72</i> gene is found in 40% of familial amyotrophic lateral sclerosis (ALS) patients. This genetic alteration has been connected with impaired management of reactive oxygen species. In this study, we conducted targeted transcriptional profiling...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2022-09-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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