Effectiveness of Pharmacokinetic-Guided Hydroxyurea Dose Individualization in Patients with Sickle Cell Anemia: A Mini-Review

• Egile Nagusiak: Joelma Santana dos Santos Neres (Egilea), Sètondji Cocou Modeste Alexandre Yahouédéhou (Egilea), Marilda Souza Goncalves (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Inconsistent therapeutic responses have been observed among patients with sickle cell anemia (SCA) undergoing hydroxyurea (HU) following the adoption of the standardized protocol. Moreover, this treatment regimen necessitates a prolonged period to reach the maximum tolerated dose in which beneficial...