Synthesis and biological evaluation of novel (E)-N'-benzylidene hydrazides as novel c-Met inhibitors through fragment based virtual screening

C-Met plays a crucial role in the development and progression of neoplastic disease. Type II c-Met inhibitors recognise the inactive DFG-out conformation of the kinase, result in better anti-tumour effects due to synergistic effect against the other kinases. According to our previous works, an (E)-N...

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Main Authors: Jing-wei Liang (Author), Shi-long Li (Author), Shan Wang (Author), Wan-qiu Li (Author), Fan-hao Meng (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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