Synthesis, Biological Evaluation, and In Silico Modeling of <i>N</i>-Substituted Quinoxaline-2-Carboxamides

• Главные авторы: Ghada Bouz (Автор), Sarah Bouz (Автор), Ondřej Janďourek (Автор), Klára Konečná (Автор), Pavel Bárta (Автор), Jarmila Vinšová (Автор), Martin Doležal (Автор), Jan Zitko (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-08-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Despite the established treatment regimens, tuberculosis remains an alarming threat to public health according to WHO. Novel agents are needed to overcome the increasing rate of resistance and perhaps achieve eradication. As part of our long-term research on pyrazine derived compounds, we prepared a...