Synthesis, Biological Evaluation, and In Silico Modeling of <i>N</i>-Substituted Quinoxaline-2-Carboxamides

• Main Authors: Ghada Bouz (Author), Sarah Bouz (Author), Ondřej Janďourek (Author), Klára Konečná (Author), Pavel Bárta (Author), Jarmila Vinšová (Author), Martin Doležal (Author), Jan Zitko (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the established treatment regimens, tuberculosis remains an alarming threat to public health according to WHO. Novel agents are needed to overcome the increasing rate of resistance and perhaps achieve eradication. As part of our long-term research on pyrazine derived compounds, we prepared a...