A study of 82 extended HLA haplotypes in <it>HFE</it>-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload

• Main Authors: Lacerda Rosa (Author), Almeida Susana (Author), Vieira Jorge (Author), Cruz Eugénia (Author), Gartner Andrea (Author), Cardoso Carla S (Author), Alves Helena (Author), Porto Graça (Author)
• Format: Book
• Published: BMC, 2006-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>It has been recently demonstrated that CD8+ T-lymphocyte numbers are genetically transmitted in association with the MHC class I region. The present study was designed with the objective of narrowing the region associated with the se...