Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

• Asıl Yazarlar: Emilie Evain-Bana (Yazar), Lucie Schiavo (Yazar), Christophe Bour (Yazar), Don Antoine Lanfranchi (Yazar), Simone Berardozzi (Yazar), Francesca Ghirga (Yazar), Denyse Bagrel (Yazar), Bruno Botta (Yazar), Gilles Hanquet (Yazar), Mattia Mori (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The cell division cycle 25 phosphatases (CDC25A, B, and C; E.C. 3.1.3.48) are key regulator of the cell cycle in human cells. Their aberrant expression has been associated with the insurgence and development of various types of cancer, and with a poor clinical prognosis. Therefore, CDC25 phosphatase...