First report of molecular diagnosis of Tunisian hemophiliacs A: Identification of 8 novel causative mutations

• Main Authors: Elmahmoudi Hejer (Author), Khodjet- (Author), Wigren Edvard (Author), Jlizi Asma (Author), Zahra Kaouther (Author), Pellechia Dorothé (Author), Vinciguerra Christine (Author), Meddeb Balkis (Author), Elggaaied Amel Ben (Author), Gouider Emna (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Introduction</p> <p>Hemophilia A is an X linked recessive hemorrhagic disorder caused by mutations in the <it>F8</it> gene that lead to qualitative and/or quantitative deficiencies of coagulation factor VIII (FVIII). Molecular diagnosis of...