Sustained antiviral response against in vitro HIV-1 infection in peripheral blood mononuclear cells from people with chronic myeloid leukemia treated with ponatinib

• Asıl Yazarlar: Mario Manzanares (Yazar), Fernando Ramos-Martín (Yazar), Sara Rodríguez-Mora (Yazar), Guiomar Casado-Fernández (Yazar), Clara Sánchez-Menéndez (Yazar), Alicia Simón-Rueda (Yazar), Elena Mateos (Yazar), Miguel Cervero (Yazar), Adam M. Spivak (Yazar), Vicente Planelles (Yazar), Montserrat Torres (Yazar), Valentín García-Gutiérrez (Yazar), Mayte Coiras (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

HIV-1 infection cannot be cured due to long-lived viral reservoirs formed by latently infected CD4+ T cells. "Shock and Kill" strategy has been considered to eliminate the viral reservoir and achieve a functional cure but the stimulation of cytotoxic immunity is necessary. Ponatinib is a t...