Synthesis and Biological Evaluation of Imadazo[1,2-<i>a</i>]pyrazines as Anticancer and Antiviral Agents through Inhibition of CDK9 and Human Coronavirus

In this work, novel imadazo[1,2-<i>a</i>]pyrazine derivatives were synthesized and evaluated as CDK9 inhibitors. The results of CDK9 assay showed that the derivatives with pyridin-4-yl in position 2 and benzyl in position 3 of imadazo[1,2-<i>a</i>]pyrazine <b>3c</b&g...

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Main Authors: Aisha A. Alsfouk (Author), Hanan M. Alshibl (Author), Bshra A. Alsfouk (Author), Najla A. Altwaijry (Author), Ebtehal S. Al-Abdullah (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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