Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions

Acamprosate is an anionic drug substance widely used in treating symptoms of alcohol withdrawal. It was recently shown that oral acamprosate absorption is likely due to paracellular transport. In contrast, little is known about the eliminating mechanism clearing acamprosate from the blood in the kid...

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Main Authors: Irina E. Antonescu (Author), Maria Karlgren (Author), Maria L. Pedersen (Author), Ivailo Simoff (Author), Christel A. S. Bergström (Author), Sibylle Neuhoff (Author), Per Artursson (Author), Bente Steffansen (Author), Carsten Uhd Nielsen (Author)
Format: Book
Published: MDPI AG, 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available