Reversible Effects of Exogenous GM3 on Meiotic Maturation and Cumulus Cells Expansion of Porcine Cumulus-oocyte Complexes

• Main Authors: Jin-Woo Kim (Author), Hyo-Jin Park (Author), Jae-Min Jung (Author), Seul-Gi Yang (Author), Min-Ji Kim (Author), In-Su Kim (Author), Ho-Geun Jega (Author), Deog-Bon Koo (Author)
• Format: Book
• Published: The Korean Society of Animal Reproduction and Biotechnology, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ganglioside GM3 is known as an inhibition factor of cell differentiation and proliferation via inhibition of epidermal growth factor receptor (EGFR) phosphorylation. Our previous study showed that the exogenous ganglioside GM3 reduced the meiotic maturation of porcine oocytes and induced apoptosis a...