Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients

• Главные авторы: Mei Meng (Автор), Rui Gao (Автор), Zixue Liu (Автор), Fengxiang Liu (Автор), Shiyu Du (Автор), Yizhi Song (Автор), Jian He (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Предметы: article
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Background: Acting as a viral entry for coronavirus to invade human cells, TMPRSS2 has become a target for the prevention and treatment of COVID-19 infection. Before this, TMPRSS2 has presented biological functions in cancer, but the roles remain controversial and the mechanism remains unelucidated....