Enhanced tumor penetration for efficient chemotherapy by a magnetothermally sensitive micelle combined with magnetic targeting and magnetic hyperthermia

• Main Authors: Yu Wang (Author), Rui Wang (Author), Lixin Chen (Author), Lili Chen (Author), Yi Zheng (Author), Yuanrong Xin (Author), Xiqiu Zhou (Author), Xiaoyun Song (Author), Jinzhou Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The high accumulation and poor penetration of nanocarriers in tumor is a contradiction of nanomedicine, which reduces the efficacy of chemotherapy. Due to the positive effect of hyperthermia on in vivo drug diffusion, we designed a magnetothermally sensitive micelle (MTM) by integrating magnetic tar...