Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage

• Main Authors: Raghda Ramadan (Author), Els Vromans (Author), Dornatien Chuo Anang (Author), Ines Goetschalckx (Author), Delphine Hoorelbeke (Author), Elke Decrock (Author), Sarah Baatout (Author), Luc Leybaert (Author), An Aerts (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundEmerging evidence indicates an excess risk of late occurring cardiovascular diseases, especially atherosclerosis, after thoracic cancer radiotherapy. Ionizing radiation (IR) induces cellular effects which may induce endothelial cell dysfunction, an early marker for atherosclerosis. In addi...