Improved Cell Selectivity of Pseudin-2 via Substitution in the Leucine-Zipper Motif: In Vitro and In Vivo Antifungal Activity

• Main Authors: Seong-Cheol Park (Author), Heabin Kim (Author), Jin-Young Kim (Author), Hyeonseok Kim (Author), Gang-Won Cheong (Author), Jung Ro Lee (Author), Mi-Kyeong Jang (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several antimicrobial peptides (AMPs) have been discovered, developed, and purified from natural sources and peptide engineering; however, the clinical applications of these AMPs are limited owing to their lack of abundance and side effects related to cytotoxicity, immunogenicity, and hemolytic acti...