In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness.

• Main Authors: Caecilia Schmid (Author), Andrea Kuemmerle (Author), Johannes Blum (Author), Salah Ghabri (Author), Victor Kande (Author), Wilfried Mutombo (Author), Medard Ilunga (Author), Ismael Lumpungu (Author), Sylvain Mutanda (Author), Pathou Nganzobo (Author), Digas Tete (Author), Nono Mubwa (Author), Mays Kisala (Author), Severine Blesson (Author), Olaf Valverde Mordt (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use, expensive (eflornithine monotherapy), or toxic, and insufficiently effective in certain areas (melarsoprol). Re...