Genetics and epigenetics of myelodysplastic syndromes and response to drug therapy: new insights

• Главные авторы: Saeid Shahrabi (Автор), Abbas Khosravi (Автор), Mohammad Shahjahani (Автор), Fakher Rahim (Автор), Najmaldin Saki (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic neoplasms ocurring mostly in the elderly. The clinical outcome of MDS patients is still poor despite progress in treatment approaches. About 90% of patients harbor at least one somatic mutation. This review aimed to assess the...