Dengue Virus-Induced Inflammation of the Endothelium and the Potential Roles of Sphingosine Kinase-1 and MicroRNAs

• Главные авторы: Amanda L. Aloia (Автор), Alexander M. Abraham (Автор), Claudine S. Bonder (Автор), Stuart M. Pitson (Автор), Jillian M. Carr (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2015-01-01T00:00:00Z.
• Предметы: article
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One of the main pathogenic effects of severe dengue virus (DENV) infection is a vascular leak syndrome. There are no available antivirals or specific DENV treatments and without hospital support severe DENV infection can be life-threatening. The cause of the vascular leakage is permeability changes...