Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia

• Principais autores: Rachel K. Toth (Autor), Noel A. Warfel (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2017-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The importance of the tumor microenvironment for cancer progression and therapeutic resistance is an emerging focus of cancer biology. Hypoxia, or low oxygen, is a hallmark of solid tumors that promotes metastasis and represents a significant obstacle to successful cancer therapy. In response to hyp...