Fibroblast activation protein-α expression in fibroblasts is common in the tumor microenvironment of colorectal cancer and may serve as a therapeutic target

• Main Authors: K. Greimelmaier (Author), N. Klopp (Author), E. Mairinger (Author), M. Wessolly (Author), S. Borchert (Author), J. Steinborn (Author), K. W. Schmid (Author), J. Wohlschlaeger (Author), F. D. Mairinger (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Colorectal cancer (CRC) is still one of the leading causes of cancer death worldwide, emphasizing the need for further diagnostic and therapeutic approaches. Cancer invasion and metastasis are affected by the tumor microenvironment (TME), with cancer-associated fibroblasts (CAF) being th...