2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

• Auteurs principaux: Antonia I. Antoniou (Auteur), Giulia Nordio (Auteur), Maria Luisa Di Paolo (Auteur), Eleonora Colombo (Auteur), Beatrice Gaffuri (Auteur), Laura Polito (Auteur), Arianna Amenta (Auteur), Pierfausto Seneci (Auteur), Lisa Dalla Via (Auteur), Dario Perdicchia (Auteur), Daniele Passarella (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

A potent nontoxic antitumor drug, 2-hydroxyoleic acid (<b>6</b>, 2OHOA) used for membrane lipid therapy, was selected as a self-assembly inducer due to its ability to form nanoparticles (NPs) in water. For this purpose, it was conjugated with a series of anticancer drugs through a disulf...