A Broad Range of Dose Optima Achieve High-level, Long-term Gene Expression After Hydrodynamic Delivery of Sleeping Beauty Transposons Using Hyperactive SB100x Transposase

The Sleeping Beauty (SB) transposon system has been shown to enable long-term gene expression by integrating new sequences into host cell chromosomes. We found that the recently reported SB100x hyperactive transposase conferred a surprisingly high level of long-term expression after hydrodynamic del...

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Hlavní autoři: Kelly M Podetz-Pedersen (Autor), Erik R Olson (Autor), Nikunj V Somia (Autor), Stephen J Russell (Autor), R Scott McIvor (Autor)
Médium: Kniha
Vydáno: Elsevier, 2016-01-01T00:00:00Z.
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