Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model

• Main Authors: William M. Parkinson (Author), Michelle Dookwah (Author), Mary Lynn Dear (Author), Cheryl L. Gatto (Author), Kazuhiro Aoki (Author), Michael Tiemeyer (Author), Kendal Broadie (Author)
• Format: Book
• Published: The Company of Biologists, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital disorders of glycosylation (CDGs) constitute a rapidly growing family of human diseases resulting from heritable mutations in genes driving the production and modification of glycoproteins. The resulting symptomatic hypoglycosylation causes multisystemic defects that include severe neurol...