Aging Exacerbates Ischemia-Reperfusion-Induced Mitochondrial Respiration Impairment in Skeletal Muscle

• Glavni autori: Stéphanie Paradis (Autor), Anne-Laure Charles (Autor), Isabelle Georg (Autor), Fabienne Goupilleau (Autor), Alain Meyer (Autor), Michel Kindo (Autor), Gilles Laverny (Autor), Daniel Metzger (Autor), Bernard Geny (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2019-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Cycles of ischemia-reperfusion (IR) that occur during peripheral arterial disease (PAD) are associated with significant morbi-mortality, and aging is an irreversible risk factor of PAD. However, the effects of advanced age on IR-induced skeletal muscle mitochondrial dysfunction are not well known. Y...