Evaluation of Solid Lipid Nanoparticles as Carriers for Delivery of Hepatitis B Surface Antigen for Vaccination Using Subcutaneous Route

• Hauptverfasser: Dinesh Mishra (Verfasst von), Himanshu Mishra (Verfasst von), Pradyumna K. Mishra (Verfasst von), Manoj Nahar (Verfasst von), Vaibhav Dubey (Verfasst von), Narendra K. Jain (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2010-11-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Purpose: Solid lipid nanoparticles (SLN) have emerged as carriers for therapeutic peptides, proteins, antigens and bioactive molecules. We have explored the potential of SLN as carrier for Hepatitis B surface antigen (HBsAg) by surface modifications to enhance their loading efficiency and the cellul...