Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125

• Main Authors: Takamichi Minato (Author), Shin Ito (Author), Bin Li (Author), Haruna Fujimori (Author), Mai Mochizuki (Author), Kazunori Yamaguchi (Author), Keiichi Tamai (Author), Muneaki Shimada (Author), Hideki Tokunaga (Author), Shogo Shigeta (Author), Ikuro Sato (Author), Hiroshi Shima (Author), Hidekazu Yamada (Author), Nobuo Yaegashi (Author), Jun Yasuda (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Ovarian cancer (OC) is an intractable gynecological tumor, and frequent recurrence is experienced within a few years even after the complete eradication of tumor tissues by radical resection and neo-adjuvant chemotherapies. The conventional recurrence marker, CA125, is widely used for fol...