Exacerbation of Intracranial Aneurysm and Aortic Dissection in Hypertensive Rat Treated With the Prostaglandin F-Receptor Antagonist AS604872

• मुख्य लेखकों: Miyuki Fukuda (लेखक), Tomohiro Aoki (लेखक), Toshiaki Manabe (लेखक), Akiko Maekawa (लेखक), Takayuki Shirakawa (लेखक), Hiroharu Kataoka (लेखक), Yasushi Takagi (लेखक), Susumu Miyamoto (लेखक), Shuh Narumiya (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2014-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract.: Intracranial aneurysm (IA) and aortic dissection are both complications of hypertension and characterized by degeneration of the media. Given the involvement of prostaglandin F2α and its receptor, FP, in extracellular matrix remodeling in a mouse model of pulmonary fibrosis, here we induc...