Sanguisorba officinalis L. suppresses non-small cell lung cancer via downregulating the PI3K/AKT/mTOR signaling pathway based on network pharmacology and experimental investigation

• Main Authors: Hong Li (Author), Jing Lin (Author), Fei Yang (Author), Junzhu Deng (Author), Jia Lai (Author), Jing Zeng (Author), Wenjun Zou (Author), Nan Jiang (Author), Qianqian Huang (Author), Hua Li (Author), Jian Liu (Author), Mao Li (Author), Zhirong Zhong (Author), Jianming Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Sanguisorba officinalis L. (SOL), a traditional Chinese herbal medicine called Diyu, has been shown to have potent antitumor effects. However, the role of SOL in suppressing NSCLC remains unknown.Methods: Network...