Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress
Pressure overload-induced pathological cardiac hypertrophy eventually leads to heart failure (HF). Unfortunately, lack of effective targeted therapies for HF remains a challenge in clinical management. Mixed-lineage leukemia 4 (MLL4) is a member of the SET family of histone methyltransferase enzymes...
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Main Authors: | Xiang-Min Meng (Author), Qiu-Yu Pang (Author), Zhen-Fang Zhou (Author), Jing-Han Yuan (Author), Lu You (Author), Qi-Pu Feng (Author), Bing-Mei Zhu (Author) |
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Format: | Book |
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Elsevier,
2024-07-01T00:00:00Z.
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