Topical Anti-Nuclear Factor-Kappa B Small Interfering RNA with Functional Peptides Containing Sericin-Based Hydrogel for Atopic Dermatitis

• Main Authors: Takanori Kanazawa (Author), Yuki Shizawa (Author), Mayu Takeuchi (Author), Kuniko Tamano (Author), Hisako Ibaraki (Author), Yasuo Seta (Author), Yuki Takashima (Author), Hiroaki Okada (Author)
• Format: Book
• Published: MDPI AG, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The small interfering RNA (siRNA) is suggested to offer a novel means of treating atopic dermatitis (AD) because it allows the specific silencing of genes related to AD pathogenesis. In our previous study, we found that siRNA targeted against RelA, an important nuclear factor-kappa B (NF-κB) subdoma...