Evaluation of the Combination of Metformin and Rapamycin in an MPP+-Treated SH-SY5Y Model of Parkinson's Disease
Metformin (MET) and rapamycin (RAPA) have been reported to protect against neurodegeneration in cellular and animal models of Parkinson's disease (PD). MET, which is a first-line drug for type 2 diabetes, and RAPA are known as mTORC1 inhibitors. MET also acts as an AMPK activator, which leads t...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2023-01-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |