Fructo-oligosaccharides alleviate inflammation-associated apoptosis of GLP-1 secreting L cells via inhibition of iNOS and cleaved caspase-3 expression

• Egile Nagusiak: Preedajit Wongkrasant (Egilea), Pawin Pongkorpsakol (Egilea), Sasirin Chitwattananont (Egilea), Wilasinee Satianrapapong (Egilea), Nuttha Tuangkijkul (Egilea), Chatchai Muanprasat (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Glucagon-like peptide 1 (GLP-1) released from enteroendocrine (L) cells regulates insulin secretion. Intestinal inflammation and impaired GLP-1 release have been found in type 2 diabetes mellitus (T2DM) patients. Fructo-oligosaccharides (FOS), a known prebiotic, improve GLP-1 release and glucose hom...