Formulation, stability testing, and analytical characterization of melatonin-based preparation for clinical trial

• Главные авторы: Samira Filali (Автор), Charlotte Bergamelli (Автор), Mamadou Lamine Tall (Автор), Damien Salmon (Автор), Diane Laleye (Автор), Carole Dhelens (Автор), Elhadji Diouf (Автор), Christine Pivot (Автор), Fabrice Pirot (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2017-08-01T00:00:00Z.
• Предметы: article
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A new institutional clinical trial assessed the improvement of sleep disorders in 40 children with autism treated by immediate-release melatonin formulation in different regimens (0.5 mg, 2 mg, and 6 mg daily) for one month. The objectives of present study were to (i) prepare low-dose melatonin hard...