Shikonin Inhibits Cancer Through P21 Upregulation and Apoptosis Induction

• Egile Nagusiak: Fangfang Wang (Egilea), Franklin Mayca Pozo (Egilea), Danmei Tian (Egilea), Xinran Geng (Egilea), Xinsheng Yao (Egilea), Youwei Zhang (Egilea), Jinshan Tang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Shikonin is a natural naphthoquinone compound and has demonstrated potent anti-cancer activities; however, the underlying molecular mechanisms remained elusive. Here we report that Shikonin inhibited the growth of a wide range of human cancer cell lines, illustrating a broad anticancer effect. Mecha...