Shikonin Inhibits Cancer Through P21 Upregulation and Apoptosis Induction

• Main Authors: Fangfang Wang (Author), Franklin Mayca Pozo (Author), Danmei Tian (Author), Xinran Geng (Author), Xinsheng Yao (Author), Youwei Zhang (Author), Jinshan Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Shikonin is a natural naphthoquinone compound and has demonstrated potent anti-cancer activities; however, the underlying molecular mechanisms remained elusive. Here we report that Shikonin inhibited the growth of a wide range of human cancer cell lines, illustrating a broad anticancer effect. Mecha...