Blocking of P2X7r Reduces Mitochondrial Stress Induced by Alcohol and Electronic Cigarette Exposure in Brain Microvascular Endothelial Cells

• Egile Nagusiak: Naveen Mekala (Egilea), Nishi Gheewala (Egilea), Slava Rom (Egilea), Uma Sriram (Egilea), Yuri Persidsky (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Studies in both humans and animal models demonstrated that chronic alcohol/e-cigarette (e-Cig) exposure affects mitochondrial function and impairs barrier function in brain microvascular endothelial cells (BMVECs). Identification of the signaling pathways by which chronic alcohol/e-Cig exposure indu...