Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• المؤلفون الرئيسيون: Wataru Nemoto (مؤلف), Kotaro Yamada (مؤلف), Osamu Nakagawasai (مؤلف), Yoshiki Ogata (مؤلف), Masato Chiba (مؤلف), Ryota Yamagata (مؤلف), Hidetomo Sakurai (مؤلف), Koichi Tan-No (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2018-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...