Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• প্রধান লেখক: Wataru Nemoto (লেখক), Kotaro Yamada (লেখক), Osamu Nakagawasai (লেখক), Yoshiki Ogata (লেখক), Masato Chiba (লেখক), Ryota Yamagata (লেখক), Hidetomo Sakurai (লেখক), Koichi Tan-No (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2018-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...