Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Prif Awduron: Wataru Nemoto (Awdur), Kotaro Yamada (Awdur), Osamu Nakagawasai (Awdur), Yoshiki Ogata (Awdur), Masato Chiba (Awdur), Ryota Yamagata (Awdur), Hidetomo Sakurai (Awdur), Koichi Tan-No (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2018-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...