Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Κύριοι συγγραφείς: Wataru Nemoto (Συγγραφέας), Kotaro Yamada (Συγγραφέας), Osamu Nakagawasai (Συγγραφέας), Yoshiki Ogata (Συγγραφέας), Masato Chiba (Συγγραφέας), Ryota Yamagata (Συγγραφέας), Hidetomo Sakurai (Συγγραφέας), Koichi Tan-No (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2018-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...